| Players | Total | Start | Sub | CO | Off | Goals |
|---|---|---|---|---|---|---|
 Thomas Strakosha | 38 | 38 | - | - | - | - |
Stefan de Vrij | 36 | 36 | 1 | - | 7 | 6 |
Lucas Leiva | 36 | 35 | 1 | 1 | 13 | 2 |
Sergej Milinkovic-Savic | 35 | 33 | 3 | 2 | 7 | 12 |
Senad Lulic | 35 | 30 | 5 | 5 | 16 | 3 |
Luis Alberto | 34 | 32 | 3 | 2 | 12 | 11 |
Ciro Immobile | 33 | 33 | - | - | 11 | 29 |
Adam Marusic | 32 | 28 | 7 | 4 | 6 | 3 |
Stefan Radu | 31 | 31 | 2 | - | 9 | - |
Marco Parolo | 31 | 30 | 1 | 1 | 4 | 4 |
Jordan Lukaku | 30 | 10 | 24 | 20 | 6 | 1 |
Felipe Caicedo | 22 | 4 | 30 | 18 | 1 | 3 |
Bastos | 21 | 16 | 18 | 5 | 5 | 4 |
Felipe Anderson | 21 | 9 | 14 | 12 | 3 | 4 |
Luiz Felipe | 18 | 12 | 23 | 6 | 1 | - |
Nani | 18 | 2 | 27 | 16 | 2 | 3 |
Alessandro Murgia | 16 | 9 | 28 | 7 | 4 | - |
Wallace | 13 | 12 | 13 | 1 | 2 | - |
Dusan Basta | 11 | 9 | 22 | 2 | 4 | - |
Patric | 11 | 4 | 28 | 7 | - | - |
Martin Caceres | 6 | 4 | 13 | 2 | - | 1 |
Davide Di Gennaro | 2 | - | 23 | 2 | - | - |
Simone Palombi | 1 | 1 | 13 | - | 1 | - |
Mauricio | 1 | - | 5 | 1 | - | - |
Filip Dordevic | - | - | 1 | - | - | - |
Wesley Hoedt | - | - | 1 | - | - | - |
Bruno Jordao | - | - | 14 | - | - | - |
Ivan Vargic | - | - | 38 | - | - | - |
Pedro Neto | - | - | 10 | - | - | - |
Guido Guerrieri | - | - | 36 | - | - | - |
Cristiano Lombardi | - | - | 1 | - | - | - |
Luca Crecco | - | - | 10 | - | - | - |
Alessio Miceli | - | - | 2 | - | - | - | 532 | 418 | 417 | 114 | 114 | 86 |
Total = Total appearances,
Start = Total started,
CO = Came on,
Sub = Started as a sub,
Off = Taken off .